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The compound has the possible to be made right into a drug to treat mucus accumulation in several typical lung diseases.
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Mucus is a significant dilemma in pulmonary drugs, simply because in people with these popular lung conditions, thick mucus can block the airways and trigger symptoms starting from a gentle cough to incredibly serious decreases in lung functionality.
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"We constructed up an image of what the secretory machinery looked like and we understood the entire key players," Dickey stated. "After we had an notion of how the many parts worked with each other, we established synaptotagmin-two (Syt2) was the top protein to target to block mucin secretion because it only results in being activated by using a significant degree of stimulation.
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